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Official publication of the Indian Society of Nephrology
 
CASE REPORT
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De Novo collapsing glomerulopathy in renal allograft in association with bk virus nephropathy in a child and stabilization of renal function by elimination of viremia


 Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr. HL Trivedi Institute of Transplantation Sciences, Ahmedabad, Gujarat, India

Correspondence Address:
DN Gera,
Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Centre, Dr. HL Trivedi Institute of Transplantation Sciences, Civil Hospital Campus, Ahmedabad - 380 016, Gujarat
India
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Source of Support: None, Conflict of Interest: None

Well-recognized association between HIV 1 infection and collapsing glomerulopathy (CG) raises the possibility that intrarenal infection by other viruses may also contribute to the development of this lesion in native or post-transplant kidneys. There is evidence in literature about association of these lesions with cytomegalovirus, Epstein–Barr virus, hepatitis C virus, and parvovirus B19 infections. Here, we present a case report of post-transplant BK virus nephropathy in a male child who was found to have CG in subsequent biopsy 2 months later. His renal function and proteinuria were stabilized on elimination of viremia.


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    -  Gera D N
    -  Shah M K
    -  Ghodela V A
    -  Kute V B
    -  Trivedi H L
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Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07