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Year : 2007  |  Volume : 17  |  Issue : 4  |  Page : 170-173

Immunoglobulin M nephropathy in familial Mediterranean fever

1 Department of Pediatric Nephrology, Izmir Tepecik Teaching and Research Hospital, Izmir, Turkey
2 Department of Pediatrics, Dokuz Eylül University Medical Faculty, Izmir, Turkey
3 Department of Pathology, Dokuz Eylül University Medical Faculty, Izmir, Turkey

Correspondence Address:
O Yavascan
9105/14 Sokak, No: 9/5, Serdar Apartmant, Akevler 35370, Yesilyurt-Izmir
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-4065.39172

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Familial Mediterranean fever (FMF) is the most common periodic syndrome characterized by various clinical manifestations associated with self-limited auto-inflammatory process. Amyloidosis is its most common renal complication that can be prevented with colchicine treatment. In the last years, further clinical and histological features of FMF nephropathy have been established, such as the associations with vasculitic diseases and various types of glomerulonephritis. IgM nephropathy (IgMN) is an uncommon histological entity that is characterized by prominent diffuse mesangial deposition of IgM. Herein, we present a 10-year-old Turkish female child suffering from FMF in which non-nephrotic proteinuria is due to IgMN other than amyloidosis.


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