Thrombotic microangiopathy with severe renal failure in adenocarcinoma

G Lakshminarayana; R Rajesh; NV Seethalekshmy; G Kurian; VN Unni

doi:10.4103/0971-4065.42342

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CASE REPORT

Year : 2008 | Volume : 18 | Issue : 2 | Page : 74-76

Thrombotic microangiopathy with severe renal failure in adenocarcinoma

G Lakshminarayana¹, R Rajesh¹, NV Seethalekshmy², G Kurian¹, VN Unni¹
¹ Department of Nephrology, Amrita Institute of Medical Sciences and Research, Kochi, India
² Department of Pathology, Amrita Institute of Medical Sciences and Research, Kochi, India

Correspondence Address:
V N Unni
Department of Nephrology, Amrita Institute of Medical Sciences and Research, Elamakkara P.O., Cochin, Kerala - 682 026
India

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/0971-4065.42342

Kidney disease frequently complicates malignancy and its treatment. The spectrum of renal disease in cancers includes acute kidney injury, chronic kidney disease and tubular disorders. Thrombotic microangiopathy (TMA) is an uncommon initial clinical presentation of malignancies. Renal failure is an extremely rare feature of cancer-associated TMA syndromes in the absence of chemotherapy. Here, we report a patient who presented to the hospital for the first time with TMA and severe renal failure requiring hemodialysis and was diagnosed with gastric adenocarcinoma.

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