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Iron status in ESRD patients
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This article was originally published by Medknow Publications and was migrated to Scientific Scholar after the change of Publisher.
Sir,
I read the recent report on iron status in ESRD patients with a great interest.[1] Jairam et al. concluded that “our ESRD patients showed marked inflammatory activation, which was more pronounced in patients who had received IV iron.”[1] I agree that the study on the ESRD patients is very interesting. I would like to add some more possible clinical explanations to the observation. Recently, Finkelstein et al. studied the correlation between hemoglobin, vitamin C, and peritoneal dialysis.[2] Indeed, the relationship between vitamin C and iron status is confirmed, and vitamin C[3] is also proposed for a possible relationship with hepcidin.[4]
References
- Iron status, inflammation and hepcidin in ESRD patients: The confounding role of intravenous iron therapy. Indian J Nephrol. 2010;20:125-31.
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- Hemoglobin and plasma vitamin c levels in patients on peritoneal dialysis. Perit Dial Int. 2011;31:74-9.
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- Iron content, bioavailability and factors affecting iron status of Indians. Indian J Med Res. 2009;130:634-45.
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