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Year : 2011  |  Volume : 21  |  Issue : 3  |  Page : 201-203

Schistosoma hematobium -associated glomerulopathy

1 Department of Nephrology, University Hospital Aristide Le Dantec, Dakar, Senegal
2 Department of Pediatrics, University Hospital Aristide Le Dantec, Dakar, Senegal
3 Department of Pathology, University Hospital Aristide Le Dantec, Dakar, Senegal

Correspondence Address:
S M Seck
Department of Nephrology, University Hospital Aristide Le Dantec, 30 Avenue Pasteur, BP 3001, Dakar
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-4065.78076

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Schistosomiasis is the second most devastating tropical parasitic disease worldwide and is responsible for many urological complications. However, glomerular injury is a rare complication mainly described with Schistosoma mansoni. We report a case of membranoproliferative glomerulonephritis (MPGN) associated with Schistosoma hematobium infection in a young Senegalese boy living in a rural area. Clinical presentation was with steroid-resistant with nephrotic syndrome. Renal biopsy showed type 1 MPGN with the presence of S. hematobium eggs surrounded by a gigantocellular granuloma. Despite therapy with antihelminthic and immunosuppressive drugs, evolution was characterized by progression to end-stage renal disease over 1 year. More efforts should be made on the prevention and early detection of schistosomiasis among at-risk populations.


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Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07