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 ORIGINAL ARTICLE
Year : 2012  |  Volume : 22  |  Issue : 3  |  Page : 193-195

Comparison of renal function between normal-weight and overweight children


1 Department of Pediatrics, Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran
2 Department of Social Medicine, Zanjan University of Medical Sciences, Zanjan, Iran

Correspondence Address:
B Falakaflaki
Department of Pediatrics, Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan
Iran
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-4065.98755

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Obesity in children is associated with hypertension, dyslipidemia, cardiovascular disease, diabetes mellitus, colon cancer, and kidney disease. Most of the studies that evaluate the association between obesity and kidney disease have been done in adults. This study was planned to compare renal function between normal-weight and overweight children. In this case-control study, 92 children (45 boys, 47 girls) aged 7-12 years were included in the analysis. 46 children (23 boys, 23 girls) with BMI 85 th percentile or greater (mean age, 9.09 years) were compared with 46 controls (22 boys, 24 girls) with BMI 5 th -84 th percentile (mean age, 8.63 years). Blood and urine sample were taken from case and control groups. Urine albumin/creatinine ratio and urine calcium/creatinine ratio and glomerular filtration rate (GFR) were determined. Children in the overweight and control groups were matched according to age and sex. Glomerular filtration rate, urine calcium/creatinine ratio, urine albumin/creatinine ratio, blood pressure, and serum creatinine were compared between normal-weight and overweight children. Our finding showed no significant difference regarding GFR, albuminuria, calciuria, blood pressure, and serum creatinine between normal-weight and overweight children.






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Indian Journal of Nephrology
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Online since 20th Sept '07