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Year : 2012  |  Volume : 22  |  Issue : 3  |  Page : 206-209

Non-nephronal hematuria misdiagnosed as C1q nephropathy: Look before you leap

1 Department of Nephrology, Medwin Hospital, Nampally, India
2 Department of Histopathology, Apollo Hospitals, Jubilee Hills, Hyderabad, Andhra Pradesh, India

Correspondence Address:
R Jha
Department of Nephrology, Medwin Hospitals, Chirag Ali Lane, Abids, Hyderabad 500 001, Andhra Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-4065.98761

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A 19-year-old male presented with persistent macroscopic hematuria for last 3 months. On initial evaluation, he was found to have minimal proteinuria, normal renal function, and normal complement with negative lupus serology. Light microscopy, immunofluorescence and electron microscopy of renal tissue confirmed the presence of C1q nephropathy. Because of poor response to immunosuppressive agent (prednisolone and mycophenolate mofetil), passage of urinary clot once and vexing persistent macroscopic hematuria, alternative diagnosis was considered. Cystourethroscopy showed urethritis of prostatic urethra. Immunosuppressives were stopped and doxycycline started to which hematuria responded dramatically. This case report illustrates that hematuria in this patient was because of undiagnosed urethritis rather than incidental C1q nephropathy.


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Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07