Hepatitis C as a potential cause of IgA nephropathy

AK Dey; A Bhattacharya; A Majumdar

doi:10.4103/0971-4065.109443

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CASE REPORT

Year : 2013 | Volume : 23 | Issue : 2 | Page : 143-145

Hepatitis C as a potential cause of IgA nephropathy

AK Dey¹, A Bhattacharya¹, A Majumdar²
¹ Department of Medicine, Advanced Medicare and Research Institute, Kolkata, India
² Department of Nephrology, Advanced Medicare and Research Institute, Kolkata, India

Correspondence Address:
A K Dey
604/D, Phase 10, New Golden Nest, Sonam Sagar Co.op Housing Society, Mira Bhayander Road, Bhayander (East), Thane, Maharashtra
India

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/0971-4065.109443

This is a case report of a 16-year-old boy presenting with a history of oliguria and anasarca. Workup revealed marked proteinuria to the tune of 8 g/day. He was subsequently found to be hepatitis C positive. Genotype was hepatitis C virus type 6. Renal biopsy revealed mesangioproliferative glomerulonephritis with IgA deposits consistent with IgA nephropathy (IgAN). Initiation of oral ribavirin and pegylated interferon caused a marked reduction in proteinuria after 8 weeks of treatment. It was postulated that hepatitis C manifested as IgAN. This case report thus sheds light on the possibility of an association between hepatitis C and IgAN.

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