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 CASE REPORT
Year : 2013  |  Volume : 23  |  Issue : 2  |  Page : 143-145

Hepatitis C as a potential cause of IgA nephropathy


1 Department of Medicine, Advanced Medicare and Research Institute, Kolkata, India
2 Department of Nephrology, Advanced Medicare and Research Institute, Kolkata, India

Correspondence Address:
A K Dey
604/D, Phase 10, New Golden Nest, Sonam Sagar Co.op Housing Society, Mira Bhayander Road, Bhayander (East), Thane, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-4065.109443

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This is a case report of a 16-year-old boy presenting with a history of oliguria and anasarca. Workup revealed marked proteinuria to the tune of 8 g/day. He was subsequently found to be hepatitis C positive. Genotype was hepatitis C virus type 6. Renal biopsy revealed mesangioproliferative glomerulonephritis with IgA deposits consistent with IgA nephropathy (IgAN). Initiation of oral ribavirin and pegylated interferon caused a marked reduction in proteinuria after 8 weeks of treatment. It was postulated that hepatitis C manifested as IgAN. This case report thus sheds light on the possibility of an association between hepatitis C and IgAN.






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Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07