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Year : 2014  |  Volume : 24  |  Issue : 6  |  Page : 394-396

Methemoglobinemia due to quinine causing severe acute kidney injury in a child

1 Department of Pediatrics, The Medicity Hospital, Gurgaon, Haryana, India
2 Kidney Institute, Medanta, The Medicity Hospital, Gurgaon, Haryana, India
3 Department of Pediatric Intensive Care, The Medicity Hospital, Gurgaon, Haryana, India

Correspondence Address:
S K Sethi
Kidney and Urology Institute, Gurgaon - 122 001, Haryana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-4065.134681

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Congenital methemoglobinemia is a rare condition resulting from a deficiency of nicotinamide adenine dinucleotide-cytochrome b5 reductase. Acquired methemoglobinemia may result due to certain drugs, chemicals and food items. Information on epidemiological determinants from India is sparse. This report describes methemoglobinemia in a 4-year-old child after parenteral administration of quinine causing acute kidney injury. This case emphasizes the need of awareness of potential adverse events of antimalarial drugs. Prompt management of methemoglobinemia is essential to avoid potential life-threatening complications.


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Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07