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Year : 2019  |  Volume : 29  |  Issue : 6  |  Page : 424-426

A rare case of acute kidney injury due to levofloxacin-induced crystal nephropathy

1 Department of Nephrology, Nizam Institute of Medical Sciences, Hyderabad, Telangana, India
2 Department of Pathology, Nizam Institute of Medical Sciences, Hyderabad, Telangana, India
3 Department of Pathology, Dr Lal PathLabs, National Reference Lab, Rohini, New Delhi, India

Correspondence Address:
Dr. Sree Bhushan Raju
Department of Nephrology, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad - 500 082, Telangana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijn.IJN_295_18

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Crystal-induced acute kidney injury (AKI) is caused by the intratubular precipitation of crystals, which results in obstruction and kidney injury. Levofloxacin is commonly used fluoroquinolone antibiotic especially for respiratory and urinary tract infections. It rarely causes any serious adverse events. Several cases of crystal nephropathy after ciprofloxacin use have been reported. Pre-existing renal dysfunction, high dose of the drug, and advanced age are considered as risk factors. To best of our knowledge, only two cases of crystal nephropathy due to levofloxacin use have been reported, we add a new one to it. The patient responded to conservative treatment with complete recovery on follow-up.


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Indian Journal of Nephrology
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Online since 20th Sept '07