| CASE REPORT |
|
| Year : 2020 | Volume
: 30
| Issue : 3 | Page : 204-206 |
Rare, yet emerging cause of graft dysfunction—ALECT 2 amyloidosis
Kulwant Singh1, Jasmine Sethi1, Rajan Duggal2, Kusum Joshi3, Arjinder S Bains4
1 Division of Nephrology, Grecian Hospital, Mohali, Punjab, India
2 Department of Histopathology, Core Diagnostics, Gurgaon, Haryana, India
3 Department of Histopathology, Medicos Centre, Chandigarh, India
4 Department of Transplant Surgery, Surya Kidney Hospital, Mohali, Punjab, India
Correspondence Address:
Dr. Kulwant Singh
Division of Nephrology, Grecian Hospital, Sector 69, Mohali - 160 062, Punjab
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijn.IJN_258_19
Amyloidosis is characterized by pathological deposition of abnormal protein aggregates in various tissues, AL protein being the commonest. Amyloidosis derived from leukocyte cell-derived chemotaxin 2 (LECT2) is a recently recognized form of amyloidosis in the United States with predominant involvement of kidney and liver. We present a case of ALECT2 renal amyloid in a transplant recipient who presented with gradual worsening of graft function and subnephrotic proteinuria. To our knowledge, this is first case of LECT2 amyloidosis from Northern India in a transplant recipient. There is no effective therapy for amyloidosis derived from leukocyte cell-derived chemotaxin 2.
[FULL TEXT] [PDF]*
|
|
Editorial Board
