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 REVIEW ARTICLE
Year : 2020  |  Volume : 30  |  Issue : 6  |  Page : 359-369

Recurrent glomerulonephritis in the kidney allograft


1 Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA
2 Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA

Correspondence Address:
Dr. Mariam P Alexander
Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 1st Street SW Rochester, Minnesota -55905
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijn.IJN_193_19

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Renal transplantation is the preferred form of renal replacement therapy in patients who develop end-stage kidney disease (ESKD). Among the diverse etiologies of ESKD, glomerulonephritis is the third most common cause, behind hypertensive and diabetic kidney disease. Although efforts to prolong graft survival have improved over time with the advent of novel immunosuppression, recurrent glomerulonephritis remains a major threat to renal allograft survival despite concomitant immunosuppression. As a result, clinical expertise, early diagnosis and intervention will help identify recurrent disease and facilitate prompt treatment, thus minimizing graft loss, resulting in improved outcomes. In this review, we highlight the clinicopathologcal characteristics of certain glomerular diseases that recur in the renal allograft.






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Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07