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Year : 2021  |  Volume : 31  |  Issue : 1  |  Page : 57-60

A rare case of APRT deficiency with end-stage renal failure and successful renal transplant

1 Department of Nephrology, Aditya Birla Memorial Hospital, Pune, Maharashtra, India
2 Department of Pathology, Apollo Hospital, Hyderabad, Telangana, India

Correspondence Address:
Dr. Tarun K Jeloka
Department of Nephrology, Aditya Birla Memorial Hospital, Pune - 411 033, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijn.IJN_202_19

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Renal calculus disease is a common cause of renal injury. However, crystal nephropathy (uric acid, oxalate, and dihydroxyadenine) can present as chronic kidney disease without any evidence of renal stones. If left undiagnosed, there is a potential chance of recurrence in the allograft leading to graft failure after transplantation. Pretransplant identification and management can avoid such complications. Here, we describe a case of APRT deficiency leading to crystal nephropathy and end-stage renal failure in a patient who underwent a successful kidney transplant.


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Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07