CASE REPORT |
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Year : 2021 | Volume
: 31
| Issue : 6 | Page : 587-591 |
Successful treatment of severe heart failure in advanced diabetic kidney disease using angiotensin–neprilysin inhibitors (sacubitril/valsartan) – report of two cases with review of options in literature
Ratan Jha1, Kiran K Mukku1, Ambati K Rakesh1, Sumeet Sinha2
1 Department of Nephrology, Virinchi Hospital, Banjara Hills, Hyderabad, Telangana, India 2 Department of Cardiology, Virinchi Hospital, Banjara Hills, Hyderabad, Telangana, India
Correspondence Address:
Ratan Jha Department of Nephrology, Virinchi HospitaL, Road No. 1, Banjara Hills, Hyderabad - 500 034, Telangana India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijn.IJN_298_20
Patients with heart failure (HF) and advanced chronic kidney disease (CKD) constitute a special population that experience poor outcomes due to poor adherence to established therapies because of potential safety concerns. Role of newer agents like angiotensin–receptor neprilysin inhibitors (ARNI) in early stages of CKD is well elucidated. We report two cases of HF with reduced ejection fraction, who received ARNI in advanced stage of CKD (stage 5) and achieved remarkable outcomes in terms of quality of life and longevity.
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