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Official publication of the Indian Society of Nephrology
 
CASE REPORT
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Challenges in management of disseminated melioidosis with endocarditis in a patient with chronic kidney disease


1 Department of Internal Medicine, Mehta Multispecialty Hospital Pvt. Ltd., Chennai, Tamil Nadu, India
2 Department of Nephrology, Mehta Multispecialty Hospital Pvt. Ltd., Chennai, Tamil Nadu, India
3 Department of Cardiology, Mehta Multispecialty Hospital Pvt. Ltd., Chennai, Tamil Nadu, India
4 Department of Microbiology, Mehta Multispecialty Hospital Pvt. Ltd., Chennai, Tamil Nadu, India
5 Department of Infectious Diseases, Mehta Multispecialty Hospital Pvt. Ltd., Chennai, Tamil Nadu, India

Correspondence Address:
Edwin Fernando,
Plot No. 1623, 9th Main Road, Ramnagar South, Madipakkam, Chennai - 600 091, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijn.IJN_185_19

Melioidosis is a tropical infection that is increasingly being reported from South India. It is frequently observed in patients with diabetes mellitus, chronic ethanol consumption and chronic kidney disease (CKD). It presents commonly with pneumonia, deep seated abscesses or osteoarticular infections. Cardiac complications are very rare with endocarditis being reported in very few patients. We report the first case of endocarditis in melioidosis in India. Although infections are common in patients with CKD, melioidosis at the time of diagnosis of CKD has never been reported in the past. Our patient had multiple liver abscesses and endocarditis, and responded well to a 6 week course of ceftazidime and doxycycline, with the latter being continued for 20 weeks.


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    -  Krishnamoorthy A
    -  Fernando E
    -  Dorairaj P
    -  Thimmaiah A
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