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Official publication of the Indian Society of Nephrology
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Renal microvascular ischemia secondary to nonsteroidal anti-inflammatory drugs

 Renal Unit, Department of Medicine, KEM Hospital, Pune, Maharashtra, India

Correspondence Address:
Vipul Chakurkar,
Renal Unit, Diamond Jubilee Building, KEM Hospital, Sardar Moodliar Road, Rasta Peth, Pune - 411 011, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijn.IJN_211_20

Nonsteroidal anti-inflammatory drugs (NSAIDs), widely prescribed for pain, can affect kidneys in various ways. We present a case of a 37-year-old woman with multiple NSAIDs intake over a short period for dysmenorrhea followed by the development of new-onset bilateral flank pain. Computed tomography revealed bilateral multiple renal infarcts. Renal function was normal. Investigations showed no cardiac or renal artery lesion and vasculitis work-up was negative. She was treated conservatively and further NSAID intake was avoided. Follow-up scan showed complete restoration of the blood flow in previously affected areas. Thus, microvascular ischemia secondary to NSAIDs was thought to be responsible.

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Indian Journal of Nephrology
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Online since 20th Sept '07