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CASE REPORT
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Catastrophic antiphospholipid syndrome in immune thrombocytopenic purpura – Beyond tenuous concomitance!


1 Department of Nephrology, Army Hospital (Research and Referral), New Delhi, India
2 Department of Nephro-Pathology, Army Hospital (Research and Referral), New Delhi, India
3 Department of Hematology, Army Hospital (Research and Referral), New Delhi, India

Correspondence Address:
Satish Mendonca,
Department of Nephrology, Army Hospital (Research and Referral), New Delhi - 110 010
India
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijn.IJN_188_19

Significance of antiphospholipid antibodies in immune thrombocytopenic purpura is debatable and pose a diagnostic and therapeutic dilemma. Catastrophic antiphospholipid syndrome is a rare life-threatening entity, occurring in patients with antiphospholipid syndrome, usually after a triggering event. We describe an adult lady of chronic immune thrombocytopenic purpura (in remission) with antiphospholipid antibodies, who presented with rapidly progressive renal failure and had primary antiphospholipid syndrome nephropathy. The index manuscript titled exemplifies the fact that although the presence of APLA in ITP is known, however, management in the absence of clinical event remains debatable and may carry a future risk of thrombotic event/s mandating close monitoring with a high index of suspicion.


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    -  Joshi A
    -  Sood V
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    -  Dogra M
    -  Batta G
    -  Tiwari R
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Indian Journal of Nephrology
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Online since 20th Sept '07