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Official publication of the Indian Society of Nephrology
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Plasmablastic Lymphoma Involving Kidney in an HIV Positive Patient: A Case Report with Review of the Literature

1 Department of Hematology and Medical Oncology, HCG Hospital, Bengaluru, Karnataka, India
2 Department of Gynae-Oncology, HCG Hospital, Bengaluru, Karnataka, India
3 Department of Pathology, HCG Hospital, Bengaluru, Karnataka, India
4 Department of Radiology, HCG Hospital, Bengaluru, Karnataka, India

Correspondence Address:
Sulav Sapkota,
HCG Towers No. 1, Kalinga Rao Road, Sampangiram Nagar, Bengaluru - 560 095, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijn.IJN_277_18

Plasmablastic lymphoma (PBL) is an aggressive lymphoma commonly associated with HIV infection. It most commonly presents in the oral cavity and rarely involves the kidney. Herein, we report a case of HIV positive male with renal involvement of PBL. The patient presented with unilateral severe hydronephrosis with unaltered renal functions. Despite aggressive management, there was an early relapse and the patient died within 2 years of the diagnosis. Despite the recent advances in the therapy of HIV-associated aggressive lymphomas, patients with PBL have a poor prognosis. Multimodal treatment with chemotherapy, newer targeted and biological agents, along with hematopoietic stem cell transplantation is essential for the treatment of PBL.

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Indian Journal of Nephrology
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Online since 20th Sept '07