Indian Journal of Nephrology About us |  Subscription |  e-Alerts  | Feedback | Login   
  Print this page Email this page   Small font sizeDefault font sizeIncrease font size
 Home | Current Issue | Archives| Ahead of print | Search |Instructions |  Editorial Board  

Users Online:152

Official publication of the Indian Society of Nephrology
Ahead of Print

IGg4-related disease presenting as rapidly progressive renal failure and inguinal iymphadenopathy

1 Associate Professor Department of Nephrology, VIMS, Bellary, Karnataka, India
2 Director at Anand Diagnostic Laboratory- A Neuberg Associate, Bengaluru, Karnataka, India
3 Consultant Pathologist at Anand Diagnostic Laboratory- A Neuberg Associate, Bengaluru, Karnataka, India
4 Junior Resident Department of Medicine, VIMS, Bellary, Karnataka, India

Correspondence Address:
Maniyar Iqbal Anvar,
Department of Nephrology, VIMS, Cantonment, Bellary, Karnataka - 583 104
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijn.IJN_377_19

A 58-year-old man presented with swelling in the left inguinal region and loss of appetite, nausea and azotemia with a serum creatinine of 5.2 mg/dL and urine albumin of 1+ and normal size kidneys with no hematuria. His serum creatinine increased to 9 mg/dL over 1 month, his total proteins were 10.8 and serum albumin was 3.3 g/dL, and lymph node excision biopsy showed fragments of lymphoid tissue with interfollicular areas containing sheets of plasma cells and atretic germinal centers. In view of unexplained renal failure, he underwent renal biopsy, which showed interstitial inflammatory infiltrate composed of lymphocytes and rich in plasma cells with storiform fibrosis and a possibility of IgG4-related renal disease was reported. On further evaluation, serum electrophoresis showed no M band. Serum IgG4 levels were 18.2 g/L (0.03–2 g/L). A diagnosis of IgG4-related renal disease was confirmed.

Print this article
  Search Pubmed for
    -  Anvar MI
    -  Iyenger JN
    -  Mehta SS
    -  Jagdeeshkumar B
 Citation Manager
 Article Access Statistics
 Reader Comments
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded2    

Recommend this journal

Indian Journal of Nephrology
Published by Wolters Kluwer - Medknow
Online since 20th Sept '07