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Baclofen-induced neurotoxicity in chronic kidney disease: Is there a safe dose?
Prem P Varma, Geet Bajpai
Department of Nephrology, Venkateshwar Hospital, Dwarka, New Delhi, India
Correspondence Address:
Prem P Varma,
A – 12, Third Floor, Sarvodaya Enclave, New Delhi - 110 017
India
 Source of Support: None, Conflict of Interest: None DOI: 10.4103/ijn.IJN_330_20
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Most cases of Baclofen toxicity have been reported in patients with impaired kidney functions, within a few days to weeks after ingestion. We report three cases of Baclofen induced encephalopathy in chronic kidney disease patients; two developed encephalopathy within 6–8 h after ingestion of a single tablet and third on 4th day of consuming 2.5 mg twice daily dose. All three cases recovered fully following haemodialysis treatment.
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