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Crescentic glomerulonephritis associated with polycythaemia vera: A rare occurrence

 Department of Nephrology, Nizams Institute of Medical Sciences, Hyderabad, Telangana, India

Correspondence Address:
Sree B Raju,
Department of Nephrology, Nizams Institute of Medical Sciences, Punjagutta, Hyderabad, Telangana - 500 082
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijn.IJN_21_20

Glomerular diseases are one of the most challenging entities in terms of diagnosis and management, especially when associated with systemic illnesses such as malignant disorders. Herein, a case of crescentic glomerulonephritis (CrGN) associated with polycythaemia vera (PV) in a 50-year-old female is described. She presented with bilateral pedal oedema, splenomegaly, renal dysfunction and severe proteinuria. On evaluation, we found PV and CrGN. Renal involvement in PV is rare and generally considered as a manifestation of hypervolemia or high-viscosity-induced renal hyper-perfusion and hyper-filtration. This is a unique case of immunologically-mediated renal disease in PV.

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Indian Journal of Nephrology
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