Intravascular hemolysis, methemogolbinemia and acute renal failure in a young female
Ashish Gupta1, Saurabh Puri2, Neeru P Aggarwal3, Gulshan S Randhwa2, Prem Mohan Jha3
1 Senior Consultant, Max Super Specialty Hospital, Vaishali, Ghaziabad, Uttar Pradesh, India
2 Medicine, Max Super Specialty Hospital, Vaishali, Ghaziabad, Uttar Pradesh, India
3 Nephrology, Max Super Specialty Hospital, Vaishali, Ghaziabad, Uttar Pradesh, India
House No 1111, Shahganj, Kujada Ka Bag, Sultanpur City, Sultanpur - 228 001, Faizabad, Uttar Pradesh
Source of Support: None, Conflict of Interest: None
Copper sulfate occurs as large blue crystals in nature, commonly known as “blue vitriol” or “blue stone.” It is a potentially lethal poison with significant mortality. Copper sulfate is a powerful oxidizing agent and causes corrosive injury to the mucous membrane. The clinical course involves intravascular hemolysis resulting in anemia, jaundice, and renal failure. Laboratory diagnosis of the condition is not an issue; the difficulty is suspecting it, promptly initiating chelation therapy, and other supportive symptomatic treatment. We present a case of copper sulfate poisoning in a young female with suicidal intent resulting in severe acute toxicity, which was successfully managed by copper chelator (d-Penicillamine) and other supportive measures.