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CASE REPORT
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Proliferative glomerulonephritis with monoclonal immunoglobulins in a child with recurrence in the allograft


1 Department of Histopathology, Apollo Hospitals, Hyderabad, Telangana, India
2 Department of Nephrology, Apollo Hospitals, Hyderabad, Telangana, India

Correspondence Address:
Swarnalata Gowrishankar,
Department of Histopathology, Apollo Hospitals, Jubilee Hills, Hyderabad - 500 096, Telangana
India
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijn.ijn_380_21

Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is among the spectrum of monoclonal protein-associated renal diseases, with only about 15 case reports in children. We report a 7-year-old boy with biopsy-proven crescentic PGNMID who progressed to end-stage renal disease within a few months of presentation. He then received a renal transplant with his grandmother as a donor. Proteinuria was detected at 27 months post-transplant and an allograft biopsy revealed a recurrent disease.


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Indian Journal of Nephrology
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Online since 20th Sept '07