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Official publication of the Indian Society of Nephrology
 
CASE REPORT
Ahead of Print

Wilson's disease presents as recurrent hypokalemic muscle paralysis


1 Assistant Professor, Department of Nephrology, Institute of Nephro-urology, Bengaluru, Karnataka, India
2 Senior Resident, Department of Nephrology, Institute of Nephro-Urology, Bengaluru, Karnataka, India
3 Associate Professor, Department of Nephrology, Institute of Nephro-urology, Bengaluru, Karnataka, India
4 Head of the Department, Department of Nephrology, Institute of Nephro-urology, Bengaluru, Karnataka, India

Correspondence Address:
Mythri Shankar,
Assistant Professor, Department of Nephrology, Institute of Nephro-Urology, Bengaluru, Karnataka
India
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijn.ijn_143_22

A 21-year-old euthyroid gentleman born to nonconsanguineous parents was diagnosed with bipolar affective disorder. He presented 4 years later with hypokalemic quadriparesis. On evaluation, he was found to have features of both proximal and distal renal tubular acidosis. Ophthalmologic examination by slit lamp confirmed the presence of the Kayser–Fleischer ring. The diagnosis of Wilson's disease was established with serum ceruloplasmin levels and 24-h urinary copper levels.Here is a rare clinical presentation of Wilson's disease in the form of hypokalemic muscle paralysis due to proximal renal tubular acidosis with distal tubule involvement. The diagnosis was delayed due to the initial presentation with psychiatric symptoms.


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Indian Journal of Nephrology
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Online since 20th Sept '07