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Year : 2012  |  Volume : 22  |  Issue : 2  |  Page : 130--132

Recombinant activated factor VII for diffuse alveolar hemorrhage in microscopic polyangiitis

SK Mandal, G Sagar, M Sahoo, S Jasuja 
 Department of Nephrology, Indraprastha Apollo Hospital, New Delhi, India

Correspondence Address:
S Jasuja
Department of Nephrology, Indraprastha Apollo Hospital, New Delhi
India

Diffuse alveolar hemorrhage is a serious complication of the small vessel vasculitis syndromes and carries a high mortality. Recombinant activated factor VII (rFVIIa) is a powerful hemostatic agent developed for treatment of bleeding in patients with hemophilia and antibodies to factors VIII or IX. It has been used increasingly in life-threatening hemorrhage in a variety of other settings in which conventional medical or surgical therapy is unsuccessful. We report the successful use of rFVIIa for massive pulmonary hemorrhage in a patient of microscopic polyangiitis, which was later complicated by thrombotic microangiopathy and posterior reversible encephalopathy syndrome.

How to cite this article:
Mandal S K, Sagar G, Sahoo M, Jasuja S. Recombinant activated factor VII for diffuse alveolar hemorrhage in microscopic polyangiitis.Indian J Nephrol 2012;22:130-132

How to cite this URL:
Mandal S K, Sagar G, Sahoo M, Jasuja S. Recombinant activated factor VII for diffuse alveolar hemorrhage in microscopic polyangiitis. Indian J Nephrol [serial online] 2012 [cited 2022 Jun 26 ];22:130-132
Available from: https://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2012;volume=22;issue=2;spage=130;epage=132;aulast=Mandal;type=0