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Year : 2015  |  Volume : 25  |  Issue : 3  |  Page : 168--170

Immunoglobulin A dominant membranoproliferative glomerulonephritis in an elderly man: A case report and review of the literature

V Agrawal1, A Kaul2, RS Ranade1, RK Sharma2 
1 Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
2 Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India

Correspondence Address:
V Agrawal
Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow - 226 014, Uttar Pradesh
India

Immunoglobulin A (IgA) dominant membranoproliferative glomerulonephritis (MPGN) is rare, described only as case reports. We report a rare case of an elderly man presenting with rapidly progressive renal failure and nephrotic range proteinuria with histological, immunofluorescence, and ultrastructural findings supporting a diagnosis of IgA dominant MPGN. Autoimmune disease, cryoglobulinemia and infection-associated glomerulonephritis were excluded. Remission was achieved within 3 months of treatment. This case highlights an uncommon diagnosis with a good response to therapy. The differential diagnosis of IgA nephropathy with MPGN-like pattern is discussed.

How to cite this article:
Agrawal V, Kaul A, Ranade R S, Sharma R K. Immunoglobulin A dominant membranoproliferative glomerulonephritis in an elderly man: A case report and review of the literature.Indian J Nephrol 2015;25:168-170

How to cite this URL:
Agrawal V, Kaul A, Ranade R S, Sharma R K. Immunoglobulin A dominant membranoproliferative glomerulonephritis in an elderly man: A case report and review of the literature. Indian J Nephrol [serial online] 2015 [cited 2021 Nov 28 ];25:168-170
Available from: https://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2015;volume=25;issue=3;spage=168;epage=170;aulast=Agrawal;type=0