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Year : 2021  |  Volume : 31  |  Issue : 3  |  Page : 261--265

Outcomes of spousal versus parental donor kidney transplants: A comparative study

Raghuram Bhat1, Sajith Narayanan1, Ismail Naduvileparambil Aboobacker1, Benil Hafeeq2, Feroz Aziz3, Sreejesh Balakrishnan1, Anjaney Yadur1, Shysil Shafeeq1, Sooraj Sasindran1, Abdul Gafoor Pacheerikuth1, NA Uvais4 
1 Department of Nephrology, Aster MIMS Hospital, Kozhikode, Kerala, India
2 Department of Nephrology, Iqraa International Hospital and Research Centre, Kozhikode, Kerala, India
3 Department of Nephrology, Aster MIMS Hospital; Department of Nephrology, Iqraa International Hospital and Research Centre, Kozhikode, Kerala, India
4 Department of Psychiatry, Iqraa International Hospital and Research Centre, Calicut, Kerala, India

Correspondence Address:
Dr. Benil Hafeeq
Department of Nephrology, Iqraa International Hospital and Research Centre, Kozhikode - 673 009, Kerala
India

Introduction: Parents and spouse constitute 70% of organ donors in India. Some centres use induction immunosuppression (IS) for all spousal transplants considering it as an immunologically high risk. This study was designed to compare the outcomes of transplant recipients who received parental donors (PDs) and spousal donors (SDs) without any induction IS. Methods: It was a retrospective study conducted at a tertiary care hospital in South India. Adults aged 18 years or above who underwent renal transplantation from a SD or PD between January 2006 and December 2016 were included in the study. Results: Our study included 154 patients with PDs and 75 patients with SDs. The mean recipient age of the PD group was 27.79 ± 6.85 years and of the SD group was 45.62 ± 7.96 years (P < 0.001). However, the follow-up period was significantly higher for the PD group (P < 0.05). There was no significant difference between acute rejection, patient loss, mean survival, graft survival (uncensored), and death censored graft survival between two groups. Conclusion: The outcomes of immunologically low-risk transplant recipients who have received PD and SD are similar and induction immunosuppression can be avoided in these patients.

How to cite this article:
Bhat R, Narayanan S, Aboobacker IN, Hafeeq B, Aziz F, Balakrishnan S, Yadur A, Shafeeq S, Sasindran S, Pacheerikuth AG, Uvais N A. Outcomes of spousal versus parental donor kidney transplants: A comparative study.Indian J Nephrol 2021;31:261-265

How to cite this URL:
Bhat R, Narayanan S, Aboobacker IN, Hafeeq B, Aziz F, Balakrishnan S, Yadur A, Shafeeq S, Sasindran S, Pacheerikuth AG, Uvais N A. Outcomes of spousal versus parental donor kidney transplants: A comparative study. Indian J Nephrol [serial online] 2021 [cited 2022 May 23 ];31:261-265
Available from: https://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2021;volume=31;issue=3;spage=261;epage=265;aulast=Bhat;type=0