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Year : 2021  |  Volume : 31  |  Issue : 4  |  Page : 386--389

Papillary renal cell carcinoma with sarcomatoid differentiation in a native kidney of transplant recipient: A case report and review of literature

Satish K Ranjan1, Ankur Mittal1, Sunil Kumar1, Sanjeev Kishore2, Tushar A Narain1, Kim J Mammen1 
1 Department of Urology, AIIMS, Rishikesh, Uttarakhand, India
2 Department of Pathology, AIIMS, Rishikesh, Uttarakhand, India

Correspondence Address:
Dr. Ankur Mittal
Department of Urology, AIIMS, Rishikesh, Uttarakhand
India

Renal cell carcinoma (RCC) developing in a transplant recipient is about 5–20 times higher than the general population. It is more common in native kidneys than graft kidney, and incidence varies between 0.3% and 4.8%. Clear cell and papillary types are more frequently reported. Most RCC of allograft recipient is usually low-grade with favorable prognosis. We present a case of papillary RCC with sarcomatoid differentiation (SD) in a native kidney of renal transplant (RT) recipient. The coexistence of sarcomatoid variant with papillary RCC, as in our case, makes it a high grade (WHO/ISUP grade 4) and portends a poor prognosis. Relative aggressiveness and rarity of this variant histology in transplant recipients prompted us to report this case and carry out an extensive search of the available literature.

How to cite this article:
Ranjan SK, Mittal A, Kumar S, Kishore S, Narain TA, Mammen KJ. Papillary renal cell carcinoma with sarcomatoid differentiation in a native kidney of transplant recipient: A case report and review of literature.Indian J Nephrol 2021;31:386-389

How to cite this URL:
Ranjan SK, Mittal A, Kumar S, Kishore S, Narain TA, Mammen KJ. Papillary renal cell carcinoma with sarcomatoid differentiation in a native kidney of transplant recipient: A case report and review of literature. Indian J Nephrol [serial online] 2021 [cited 2021 Oct 20 ];31:386-389
Available from: https://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2021;volume=31;issue=4;spage=386;epage=389;aulast=Ranjan;type=0