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Year : 2021  |  Volume : 31  |  Issue : 5  |  Page : 442--448

Clinical profile and outcome of hemodialysis patients with SARS COV2 infection in a tertiary care centre in Mumbai, India

Smriti Sinha, Rudramani Swami, Ahmad Shakir, Sayed Salman Ali, Jyoti Bansode, Kalpana Mehta 
 Department of Nephrology, Topiwala Nair Medical College and BYL Nair Hospital, Mumbai, Maharashtra, India

Correspondence Address:
Dr. Rudramani Swami
803B, Aricia Altis, Near APMC Market and Fortis Hospital, Bail Bazar, Kalyan West, Thane, Maharashtra
India

Introduction: CKD5D is a high risk subgroup with high comorbidity burden, need for frequent visits to dialysis centre and a compromised immune system. The effect of SARS COV2 virus on this population is not well known. Methods: This prospective study enrolled, all CKD5D with COVID 19 infection, admitted to our hospital, from 23rd April to 30th June 2020 & whose outcome as discharge/mortality was known. Their clinical profile, investigations, treatment and outcome in terms of mortality or discharge after clearing infection was noted and analysed. Results: Total 203 dialysis patients with COVID 19 were referred to our institute. Of these total, 131 were analysed. Median age was 50 years (19-80 years) with 57% were males. Hypertension (76%) was the commonest comorbidity followed by diabetes (29%) and coronary artery disease (22%). Dyspnoea, fever and cough were present in 50%, 40%, and 33% patients respectively. 26% were asymptomatic. None had dialyser clotting. Mortality was 20.6%. Time to turn RT PCR negative was 14 days (3-40 days). Comparing deceased vs survivors: Age [56 vs 49 yrs], diabetes [56% vs 22%], duration of symptoms at admission [5 vs 4 days], dyspnea [85% vs 40%] and encephalopathy [30% vs 1%] at admission, bilateral opacities on Chest X ray [93% vs 20%] and high leucocyte count [11,059 ± 5,929 vs 7,022 ± 2,935/cmm] were statistically significant variables associated with mortality. Conclusion: Asymptomatic group was 26% of the total CKD5D with COVID 19 infection population analysed. Mortality was 20.61%. Higher age, later presentation to hospital, diabetes, dyspnoea, & encephalopathy at presentation, bilateral opacities on Chest X- Ray & higher leukocyte counts were significantly associated with mortality.

How to cite this article:
Sinha S, Swami R, Shakir A, Salman Ali S, Bansode J, Mehta K. Clinical profile and outcome of hemodialysis patients with SARS COV2 infection in a tertiary care centre in Mumbai, India.Indian J Nephrol 2021;31:442-448

How to cite this URL:
Sinha S, Swami R, Shakir A, Salman Ali S, Bansode J, Mehta K. Clinical profile and outcome of hemodialysis patients with SARS COV2 infection in a tertiary care centre in Mumbai, India. Indian J Nephrol [serial online] 2021 [cited 2021 Dec 9 ];31:442-448
Available from: https://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2021;volume=31;issue=5;spage=442;epage=448;aulast=Sinha;type=0