Indian J Nephrol Close
 

Figure 1: (a and b) Hematoxylin–eosin-stained bone marrow trephine biopsy section from the case demonstrating normocellular marrow with morphologically normal maturing myeloid elements and megakaryocytes with near-total absence of erythroid islands (maturation arrest). (c) Note there is marked reduction in erythroid islands as highlighted by lack/absence of glycophorin staining by immunohistochemistry (peroxidase–antiperoxidase). Note the background RBCs in the section which serve as positive internal control for glycophorin (original magnification: a, ×200; b and c, ×400)

Figure 1: (a and b) Hematoxylin–eosin-stained bone marrow trephine biopsy section from the case demonstrating normocellular marrow with morphologically normal maturing myeloid elements and megakaryocytes with near-total absence of erythroid islands (maturation arrest). (c) Note there is marked reduction in erythroid islands as highlighted by <b>lack/absence</b> of glycophorin staining by immunohistochemistry (peroxidase–antiperoxidase). Note the background RBCs in the section which serve as positive internal control for glycophorin (original magnification: a, ×200; b and c, ×400)