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Figure 3: Proliferative glomerulonephritis with monoclonal immunoglobulin deposits: The glomerulus shows a mesangioproliferative pattern of injury with a small segmental scar (a; PAS 400×). The immunofluorescence studies are characteristic with bright granular peripheral capillary wall staining with IgG. The IgG subtype studies demonstrated IgG3 restricted staining (b; 200×). The glomeruli demonstrate kappa light chain restriction (c; 400×) without lambda light chain (d; 400×)

Figure 3: Proliferative glomerulonephritis with monoclonal immunoglobulin deposits: The glomerulus shows a mesangioproliferative pattern of injury with a small segmental scar (a; PAS 400×). The immunofluorescence studies are characteristic with bright granular peripheral capillary wall staining with IgG. The IgG subtype studies demonstrated IgG3 restricted staining (b; 200×). The glomeruli demonstrate kappa light chain restriction (c; 400×) without lambda light chain (d; 400×)