Indian J Nephrol Close
 

Figure 1: (a) Plain CT scan neck, axial section showing a large lobulated isodense lesion (6.9 × 4.5 cm) involving the thyroid cartilage (arrows), causing its destruction with compression and displacement of the vocal cords medially, resulting in luminal narrowing at the level of glottis. (b) FNAC from thyroid cartilage mass showing diffusely scattered cells mostly consisting of plasma cells and few lymphocytes. Few plasma cells show binucleated and multinucleated forms (*). The cells show moderate amount of amphophilic cytoplasm with dark round eccentric nuclei. These features are consistent with plasma cell neoplasm (hematoxylin and eosin stain, ×20). (c) Bone marrow aspiration smear showing hypercellular marrow containing predominantly plasma cells (70%–80%) with markedly decreased normal marrow elements. The plasma cells show abundant cytoplasm and large eccentric vesicular nucleus, with perinuclear halo, and few show prominence of nucleoli. Few binucleated and multinucleated plasma cells are seen (*) (Giemsa stain, ×40) CT = computed tomography, FNAC = fine-needle aspiration cytology

Figure 1: (a) Plain CT scan neck, axial section showing a large lobulated isodense lesion (6.9 × 4.5 cm) involving the thyroid cartilage (arrows), causing its destruction with compression and displacement of the vocal cords medially, resulting in luminal narrowing at the level of glottis. (b) FNAC from thyroid cartilage mass showing diffusely scattered cells mostly consisting of plasma cells and few lymphocytes. Few plasma cells show binucleated and multinucleated forms (*). The cells show moderate amount of amphophilic cytoplasm with dark round eccentric nuclei. These features are consistent with plasma cell neoplasm (hematoxylin and eosin stain, ×20). (c) Bone marrow aspiration smear showing hypercellular marrow containing predominantly plasma cells (70%–80%) with markedly decreased normal marrow elements. The plasma cells show abundant cytoplasm and large eccentric vesicular nucleus, with perinuclear halo, and few show prominence of nucleoli. Few binucleated and multinucleated plasma cells are seen (*) (Giemsa stain, ×40) CT = computed tomography, FNAC = fine-needle aspiration cytology