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 CASE REPORT
Year : 2010  |  Volume : 20  |  Issue : 4  |  Page : 211-213

Collapsing glomerulopathy in an HIV-positive patient in a low-incidence belt


1 Department of Pathology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu & Kashmir, India
2 Department of Nephrology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu & Kashmir, India

Correspondence Address:
M S Najar
HOD Nephrology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu & Kashmir
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-4065.73451

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Human immunodeficiency virus (HIV) involves glomerular, tubulointerstitial, and vascular compartments of the kidney. The most common glomerular lesion is HIV-associated focal segmental glomerulosclerosis (FSGS) and related mesangiopathies collectively termed HIV-associated nephropathy (HIVAN). A variety of immune-complex mediated glomerular diseases such as membranoproliferative glomerulonephritis (MPGN), IgA nephropathy, and lupus-like glomerulonephritis also occur. HIVAN is restricted to patients presenting with proteinuria and progressive reduction of renal function and with distinctive but not pathognomonic pathology (FSGS often coexisting with glomerular collapse and tubular microcystic dilatations). The worldwide incidence of collapsing glomerulopathy (CG) in HIV-positive patients is high in Americans. But in India and other Asian countries, other forms of kidney diseases are more commonly seen. We report the first case of CG in the state of Jammu and Kashmir which also happens to be a very low incidence belt for HIV.






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